L-selenomethionine powder

SHAANXI YUANTAI BIOLOGICAL TECHNOLOGY CO., LTD.: L-selenomethionine Powder Manufacturer kunye noMboneleli

I-Shaanxi Yuantai Biotechnology Co., Ltd. ngumvelisi ohamba phambili kunye nomthengisi we- L-selenomethionine powder ekumgangatho ophezulu , kwaye siyaziqhenya ngayo. Izixhobo zethu eziphambili, ulawulo oluqinileyo lomgangatho, kunye nokuzinikela ekuveliseni izinto ezintsha kusenza sibonakale kweli shishini. Sikhethe, kwaye siya kukunika ubunyulu obungenakuthelekiswa nanto, ukuhambelana, kunye nokuthembeka ukuhlangabezana neemfuno zakho.

Kutheni ukhetha i-L-selenomethionine powder yethu?

Khetha Shaanxi Yuantai Biotechnology Co., Ltd., ukhetha ukugqwesa. Umgubo wethu we-L-selenomethionine ubalasele ngezi zinto zilandelayo:

1. Ucoceko oluphezulu: ludlula imigangatho yoshishino
2. Umgangatho ohambelanayo: i-batch-to-batch consistency
3. Ukuthotyelwa kokulawula: idibana ne-FDA, i-EFSA kunye neminye imigangatho yehlabathi
4. Izatifikethi ezininzi: i-EU kunye neNorth American organic certification, ISO22000, Kosher certification, Halal certification, HACCP certification
5. Ikhonkco lokubonelela elithembekileyo: qinisekisa imveliso engaphazamisekiyo

Intshayelelo ye-L-selenomethionine Powder

L-selenomethionine powder ngumgubo oqinileyo omhlophe ukuya kumhlophe kubushushu begumbi kunye noxinzelelo. Ine-solubility ethile emanzini kwaye iyanyibilika kwi-alcohol organic solvents, kodwa kunzima ukuyinyibilika kwi-ether organic solvents. Yinto ye-chiral amino acid kwaye ikwayeyona ndlela yokutya yendalo yeselenium. Inemisebenzi eyahlukeneyo yomzimba, kubandakanya ukuqinisa ukuhamba kwedlozi, ukunyusa amandla omzimba we-antioxidant kunye nokuphucula ukhuselo lomzimba. Inendima ebalulekileyo kwinkalo yophando olusisiseko lwe-biochemistry. Isicelo esihle.
Yi-selenochiral amino acid equlethe iyunithi ye-amino acid esebenzayo kwisakhiwo sayo kwaye ineempawu eziqhelekileyo zomzimba kunye neekhemikhali zezinto eziqhelekileyo ze-amino acid. Iyakwazi ukusabela ngombala obalulekileyo ngezinto ze-ninhydrin. Ngenxa yobukho be-selenium, i-L-selenomethionine inomdla kwizinto eziqhelekileyo ze-oxidants, kwaye ijwayele ukuchithwa kwe-oxidative xa ibonakaliswe kwii-oxidants. Yi-L-isomer ye-selenomethionine kwaye yeyona ndlela yokutya yendalo ye-selenium. Inokunyusa ukubonakaliswa kwe-glutathione peroxidase. Yeyona ndlela ibalulekileyo yendalo yeselenium efumaneka kwindalo. Inokuveliswa ngenkqubo yokudibanisa imichiza emihle. Imveliso inezithako ezikhethekileyo, ukucoceka okuphezulu (≥98%) kunye ne-bioavailability ephezulu.
Njengesongezo sokutya kwiinkukhu kunye nemfuyo, i-selenoamino acids ineempawu zokuphucula umgangatho weenkukhu kunye nemveliso yemfuyo, ukuphucula amandla okuzala kwezilwanyana, ukuphucula izinga lomzimba, izinga eliphezulu lokufunxa, kunye nomsebenzi onamandla webhayoloji. Ine-bioavailability ephezulu kwaye inokubonelela ngokufanelekileyo i-selenium efunwa ngumzimba womntu. Ithathwa njengenye yezongezo ezikhuselekileyo ze-selenium.

Indlela yokudibanisa

Iindlela eziqhelekileyo ziquka indlela ye-ammonia yamanzi, indlela ye-methyllithium, indlela ye-aminobutyrolactone hydrobromide, indlela ye-methylselenylpropionaldehyde, indlela ye-dihaloethylpiperidinedione, njl.

1. Ukuqala kwi-methionine, i-compound ekujoliswe kuyo ifunyenwe nge-reaction ye-7-step reaction. Isivuno sisonke singaphantsi kwama-30%. Inkqubo isebenzisa ii-reagents zeekhemikhali ezibizayo ezifana ne-methyllithium (enokutsha kakhulu) kunye ne-tributoxyboron, kwaye kukho inyathelo elinye kwinkqubo. Ukusebenzisa i-hydrobromide halogenation phantsi kweemeko eziqinileyo ze-acidic kufuna iimeko ze-anhydrous kunye ne-anaerobic. Iimfuno zezixhobo kunye nokusebenza ziphezulu kakhulu, okwenza kube nzima ukufikelela kwimveliso enkulu.

2. Ukuqala kwi-γ-butyrolactone, imveliso ekujoliswe kuyo yenziwe ngamanyathelo amahlanu aquka i-bromination, i-amination, kunye nokudibanisa. Inkqubo yokudibanisa imi ngolu hlobo lulandelayo. I-reaction ekugqibeleni ifumana i-DL selenomethionine, kunye nesivuno se-33%. Nangona kunjalo, le ndlela yokudibanisa isebenzisa i-bromine engamanzi enetyhefu kakhulu, ekunzima ukuyisebenzisa kwaye ifuna izixhobo eziphezulu.

3. Ineenzuzo zokuvunwa kwemveliso ephezulu, inkqubo elula yokudibanisa, ukufumaneka lula kwemathiriyeli ekrwada, iimeko zokusabela ezithambileyo, kunye noshishino olulula. I-synthesis yahlulwe yangamanyathelo amabini. Amanyathelo athile: sebenzisa i-homoserine ye-DL njengento ekrwada, yongeza isisombululo se-hydrobromic acid, epholile kwiqondo lokushisa emva kokuba i-reaction iphelile, ipholile kwaye i-crystallize, ihluzo, kwaye ufumane i-DL 2 amino 4-bromobutyric acid hydrogen bromide. Ityuwa ye-asidi, indlela yokusabela imi ngolu hlobo lulandelayo:

Emva koko, sebenzisa i-ethanol njenge-solvent, ngokukhawuleza ungeze i-selenium powder kwi-NaBH4 phantsi kwe-ice bath, kwaye ufumane i-NaHSe emva kokuba impendulo iphelile; ke ngokucotha wongeza i-NaHSe dropwise kwi-DL 2 amino 4-bromobutyric acid hydrobromide kwiqondo lobushushu begumbi. Emva kokusabela kwiyure enye, kancinane yongeza i-methyl iodide dropwise ukuqhubeka ne-reaction de igqibe, lungisa ixabiso le-pH lesisombululo sokusabela kwi-1-5, kunye ne-dehydrate ukuze ufumane imveliso ekujoliswe kuyo i-DL selenomethionine. Ifomula yokusabela imi ngolu hlobo lulandelayo:

Amanyathelo okulinga athile alandelayo: (1) I-Synthesis ye-DL 2 amino 4-bromobutyric acid hydrobromide: Kwi-kettle yokusabela, yongeza i-0.60 kgDL i-homoserine, kwaye ngexesha elifanayo yongeza i-ethanol kunye namanzi kwi-volume ratio ye-1: 1. Xuba i-solvent 2L, yongeza i-2.0kg (ubuninzi: 1.38g / cm3) 40% i-hydrobromic acid, ukushisa ukuya kwi-70 ° C kwi-1.5h, ipholile kwiqondo lokushisa, i-crystallize ngokupholisa, ihluzo ukufumana i-DL 2 amino 4-bromobutyrate hydrogen Bromate, isivuno 90%.
(2) I-Synthesis ye-NaHSe: Ngaphantsi kwe-ice bath, yongeza i-0.19 kg ye-NaBH4 kwi-1L isisombululo se-ethanol, ngokukhawuleza ungeze i-0.79 kg Se powder, kwaye udibanise isixhobo sokulinganisela uxinzelelo lomoya ngexesha elifanayo. Emva kokuba udibaniso lwedropwise lugqityiwe, qhubeka ne-incubation reaction kwiyure enye.
(3) I-synthesis ye-DL selenomethionine: Kwi-kettle ye-5L yokuphendula, ngokukhawuleza yongeza i-NaHSe efunyenwe kwisinyathelo (2) kwi-DL 2 amino 4-bromobutyric acid hydrobromide efunyenwe kwisinyathelo (1), Emva kokuphendula iyure ye-1, qhubeka ngokuthe ngcembe. yongeza 0.64 kg iodomethane dropwise. Emva kokusabela kwiqondo lokushisa kwegumbi kwiiyure ze-12, lungisa ixabiso le-pH kwi-5, ihluzo kunye ne-dehydrate, kwaye ufumane imveliso ejoliswe kuyo emhlophe ye-DL selenomethionine imveliso kunye nesivuno se-86%.
Ingundoqo yendlela yokwenziwa yale ndlela ixhomekeke kwisizukulwana se-nucleophilic NaHSe kwaye igqibezela ukuguqulwa kwamanyathelo abalulekileyo. Le ndlela yokudibanisa ineenzuzo zokuvunwa kwemveliso ephezulu, inkqubo elula yokudibanisa, izinto ezifumaneka lula ekrwada, iimeko zokusabela kancinci, kunye noshishino olulula.

Ukusebenza

1. Isiphumo se-Antioxidant: Yi-antioxidant enamandla enokunceda umzimba ukuba ususe ii-radicals zamahhala kunye nokukhusela iiseli kumonakalo we-oxidative. Ukongeza, inokuphucula amandla e-antioxidant yeeseli kwaye ithintele ukufa kweeseli okubangelwa kukusabela kwe-oxidative.
2. Ukuphucula impilo ye-cardiovascular
Inokunciphisa amanqanaba e-cholesterol egazini kwaye inciphise idiphozithi yamafutha kwimithambo yegazi, ngaloo ndlela inciphisa umngcipheko wesifo sentliziyo. Ngexesha elifanayo, kunokunciphisa amanqanaba e-fibrinogen egazini kwaye kuthintele ukubunjwa kwamahlwili egazi.
3. Yandisa ukhuseleko
Inokomeleza ukhuseleko lomzimba, yandise ukusebenza kweeseli ezimhlophe zegazi, ize yandise nokuveliswa kwezilwa-buhlungu. Ukongeza, inokukhuthaza umsebenzi we-T lymphocytes kunye nokuphucula ukuxhathisa komzimba.
4. Khuthaza ukukhula nophuhliso
Kubantwana, idlala indima ebalulekileyo ekukhuleni nasekuphuhliseni inkqubo. Kunokukhuthaza ukukhula kwamathambo, ukomeleza izihlunu, kwaye kwenza abantwana bakhule besempilweni.
5. Eminye imisebenzi
Ukongeza kwezi ziphumo zingentla, i-L-selenomethionine nayo ineempembelelo zesibindi ezichasene ne-fatty, impembelelo ethile yokukhusela kwi-myocardium, imiphumo ye-antihypertensive kunye ne-antidepressant properties.

UkuQulunqa

Ukuqulunqwa kweCapusle

Ukwenziwa kweCwecwe

Ifomula yesiselo esiqinileyo

iziqinisekiso

I-YTBIO iphuhla ngendlela ejikelezayo. Sinefektri yethu, ukuhlolwa komgangatho kunye neqela le-R&D. Sizimisele ukubonelela abathengi ngomgangatho ogqwesileyo L-selenomethionine powder kunye neenkonzo. Yinjongo yethu yantlandlolo ukuvumela wonke umthengi ukuba akonwabele umgangatho ophezulu kunye neemveliso ezisempilweni. Ukuba unayo nayiphi na iimfuno okanye imibuzo malunga neemveliso zethu, nceda uzive ukhululekile ukuqhagamshelana nathi kwaye siya kukuphendula ngokukhawuleza.

Ukupakisha nokuthumela

Sinikezela ngeendlela zokupakisha eziguquguqukayo ukuze zihambelane neemfuno zakho, ukusuka kumanani amancinci ukuya kwii-odolo ezininzi. Iqela lethu lolungiselelo liqinisekisa ukuhanjiswa okukhuselekileyo nangexesha, ukugcina imfezeko yemveliso kulo lonke uthutho.

Inkampani yethu kunye neFactory

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Imibuzo ebuzwa qho

Umbuzo: Yintoni ubomi beshelufu?
A: Ngaphantsi kweemeko ezifanelekileyo zokugcina, imveliso yethu igcina uzinzo ukuya kwiinyanga ezingama-24.

Umbuzo: Ngaba unokubonelela ngeefomyula eziqhelekileyo?
A: Ewe, iqela lethu le-R&D lingasebenza nawe ukuphuhlisa izisombululo ezilungiselelweyo.

Q: Zeziphi iziqinisekiso enazo imveliso yakho?
A: Imveliso yethu iqinisekiswe yi-EU&NOP Organic, ISO22000, Kosher, Halal, kunye ne-HACCP.

Qhagamshelana nathi

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