Shikimic Acid Powder

Yintoni i-shikimic acid?

I-Shikimic Acid Powder yi-white crystalline powder enyibilika lula emanzini. Ithiywe emva kokuba yahlulwe okokuqala kwi-M. japonica kwaye yi-metabolite ebalulekileyo yezityalo kunye neentsholongwane. Kangangexesha elide, i-shikimic acid ibisoloko ikhutshwa kwiziqhamo ezomisiweyo nezivuthiweyo ze-star anise okanye i-Japanese shiki (i-Japanese anise). Kwiminyaka yakutshanje, kukwakho neengxelo zophando malunga nokukhutshelwa kwe-shikimic acid kwiziqhamo ze-North American liquidambar kunye neenaliti zephayini.

Umthombo wesityalo

I-asidi ye-Shikimic ifumaneka kwiziqhamo ezomileyo nezivuthiweyo ze-star anise, isityalo kwintsapho yaseMagnoliaceae. I-anise ngumthi oluhlaza okhula kwindawo efumileyo, efudumeleyo enomthunzi kwaye unokufikelela kubude obuziimitha ezingama-30. Isasazwa kakhulu kwiindawo zeentaba ezinomhlaba okhululekileyo eFujian, Guangdong, Guangxi, Yunnan, Guizhou nakwamanye amaphondo. Ixolo lingwevu ukuya kumdaka obomvu. Amagqabi a-oval, aphelele, a-lanceolate ekukhuleni, isikhumba, ubude obufutshane, ubude be-6-12 cm, ububanzi obuyi-2-5 cm, kunye namabala e-oyile acacileyo abonakala phezulu. Iintyatyambo entwasahlobo nasekwindla. Iintyatyambo zihlala zodwa kwii-axils zamagqabi. Kukho iisepal ezi-3 ezityheli-luhlaza; 6-9 perianths, ipinki ukuya kubomvu obunzulu. Iziqhamo ukusuka ekwindla ukuya entwasahlobo kunyaka ozayo. Isiqhamo esihlanganisiweyo simile okwenkwenkwezi kunye ne-octagonal, 1-2 cm ubude, 3-5 cm ububanzi, kunye ne-1 cm ukuphakama. Ijika ukusuka eluhlaza ukuya kumthubi xa sele ikhulile. Umphezulu we-follicles u-blunt okanye u-blunt-point, kwaye nganye iqulethe imbewu ye-6 mm ende. Iziqhamo zivunwa ekwindla nasebusika kwaye zijike zibebomvu-mdaka okanye tyheli-mdaka emva kokoma. Ivumba liyanuka kwaye liswiti. IMangcao, nekwaziwa njenge anise yasendle, sisihlahla esihlala siluhlaza unyaka wonke. Imbewu imdaka okhanyayo kwaye imenyezela. Ixesha leentyantyambo lingoMeyi kwaye ixesha leziqhamo liqala ngoSeptemba ukuya kuOktobha. Isasazwa kakhulu kwihlathi leenduli ezingenanto kunye nemithambeka engaphantsi kwe-1200 yeemitha. Ithwala isiqhamo ekwindla. , isiqhamo siqulethe isixa esikhulu se-shikimic acid. Isiqhamo sifana kakhulu ne-star anise, kodwa inetyhefu, ngoko ke ukudideka kufuneka kugwenywe.

Ziziphi iingenelo?

I-Shikimic Acid Powder yi-monomeric compound enefuthe lokulwa nokuvuvukala kunye ne-analgesic, kwaye ingasetyenziswa njengeyeza lokulwa neentsholongwane. I-Shikimic acid ichaphazela imetabolism ye-arachidonic acid, ithintela ukuhlanganiswa kweeplatelet, kwaye ithintela ukwakheka kwe-arterial kunye ne-venous thrombosis kunye ne-cerebral thrombosis. Uphando lokuqala olwenziwe yi-Pharmacology Research Laboratory yaseBeijing University of Chinese Medicine lufumanise okokuqala ukuba i-shikimic acid inefuthe elibalulekileyo lokulwa ne-thrombotic kwaye inokuthintela ukwakheka kwe-arterial kunye ne-venous thrombosis kunye ne-cerebral thrombosis. Ukuze kucaciswe indlela yayo yokulwa ne-thrombotic, abaphandi bafunde isiphumo se-shikimic acid kwi-platelet aggregation kunye ne-coagulation, kwaye bahlalutya ubudlelwane phakathi kwendlela esebenza ngayo kunye ne-arachidonic acid metabolism. Iziphumo zibonisa ukuba i-shikimic acid inokuba nefuthe lokulwa ne-thrombotic ngokuchaphazela imetabolism ye-arachidonic acid, ithintele ukuhlanganiswa kweeplatelet, kwaye ithintele inkqubo ye-coagulation.

(1) Isiphumo sokulwa neentsholongwane:

Uphononongo luye lwaxela ukuba i-asidi ye-shikimic ingasetyenziswa njengemveliso yoqobo yokwenza ii-snowflakes ze-ceylon (izinto ze-polyoxycyclohexane). Le derivative inokuthintela kakhulu ukuhanjiswa kwe-nucleotides kwi-Eichli ascites iiseli zomhlaza kwaye inefuthe kwiiseli zomhlaza ezikhuliswe kwi-vitro. Iiseli ziyityhefu.

(2) Iimpembelelo ezichasayo kunye ne-analgesic:

Ngophando lovavanyo, uXing Jianfeng kunye nabanye bafumanisa ukuba i-isopropylshikimic acid (ISA) ayinakunqanda kuphela ukuphuma kunye ne-edema kwinqanaba lokuqala lokudumba, kodwa ikwanqanda ukwanda kwezicubu kunye nokwakheka kwezicubu zegranulation kwinqanaba lokugqibela lokudumba, kwaye ineempembelelo ezichasayo ezicacileyo.

(3) Isiphumo sokulwa ne-thrombotic:

Uphando lwangaphambili lwe-Pharmacology Research Laboratory yaseBeijing yeYunivesithi yaseChina yeMithi yafumanisa okokuqala ukuba i-asidi ye-shikimic ineempembelelo ezichasene ne-thrombotic kwaye inokuthintela ukubunjwa kwe-arterial kunye ne-venous thrombosis kunye ne-cerebral thrombosis. I-asidi ye-Shikimic inokuthintela ukuhlanganiswa kweplatelet kunye ne-coagulation inkqubo ngokuchaphazela i-arachidonic acid metabolism, ngaloo ndlela isebenzise i-anti-thrombotic effects.

(4) Isiphumo sokulwa nomkhuhlane weentaka: I-Oseltamivir (i-Tamiflu), i-neuraminidase inhibitor eveliswe yinkampani yaseSwitzerland i-Roche, lichiza elitsha lentsholongwane yomkhuhlane. Uphononongo lovavanyo lubonise ukuba lunempembelelo yokuthintela kwiintsholongwane zomkhuhlane weentaka i-H5N1 kunye ne-H9N2. , kunye ne-asidi ye-shikimic yinto ebalulekileyo ekrwada kwi-synthesis ye "Tamiflu" kwaye inokwenziwa ngokuguqula isakhiwo se-shikimic acid. Ezi xabiso zonyango ze-shikimic acid ziyenza ibe nexabiso elihle lezoqoqosho.

Ulwalathiso lwesicelo

I-Shikimic Acid Powder yeyona nto iphambili ekuhlanganisweni kwee-alkaloids ezininzi, ii-arylamine acids, ii-indole derivatives kunye namayeza e-chiral. Kutshanje, i-shikimic acid isetyenzisiwe njengesixhobo sokuqala se-oseltamivir (isithako esisebenzayo seTamiflu), i-neuraminidase inhibitor enokusetyenziswa ukunyanga nokuthintela i-influenza A kunye ne-influenza B.

I-Shikimic Acid Khungani

I-Yuantai Organic Bio izibophelele ekuboneleleni abathengi nge- Shikimic Acid Powder ekumgangatho ophezulu kunye neenkonzo ukuze wonke umthengi akwazi ukonwabela ukutya kwendalo, okunempilo, nokusemgangathweni ophezulu. Ukuba unemibuzo okanye iimfuno malunga neemveliso zethu, nceda uzive ukhululekile ukunxibelelana nathi, kwaye siya kukuphendula ngokukhawuleza.

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