Tirzepatide Powder Ubuninzi

Umthengisi weTirzepatide Powder 98% wezinto ezikrwada

I-YTBIO ibonelela nge-98% yePowder yeTirzepatide ecocekileyo. Nceda unxibelelane nathi ukuze ufumane ulwazi ngemveliso kunye namaxabiso amva nje. I-Tirzepatide Powder Bulk sisithako se-synthetic peptide active pharmaceutical (API), esiyinxalenye ye-dual receptor agonists ye-GIP (i-glucose-dependent insulinotropic peptide) kunye ne-GLP-1 (i-glucagon-like peptide-1).

I-Tirzepatide isebenza ngaxeshanye kuzo zombini ii-receptors ze-GIP kunye ne-GLP-1. Zombini ezi ndlela ze-hormone ezivela emathunjini zibandakanyeka ekukhutshweni kwe-insulin exhomekeke kwi-glucose, ekulawuleni inkanuko, nakwi-metabolism yamandla. Xa kuthelekiswa ne-agonists ye-receptor ye-GLP-1 ekhethiweyo, i-tirzepatide, ngokusebenza kuzo zombini ii-receptors ngaxeshanye, yenza indlela eyahlukileyo yokusebenza kabini, okwenza ukuba ibe yinxalenye ebalulekileyo kuphando ngesifo seswekile, ukutyeba kakhulu, kunye nezifo ezinxulumene ne-metabolism. Izifundo zeklinikhi zibonise ukuba i-tirzepatide inefuthe elibalulekileyo ekuphuculeni ulawulo lwe-glycemic kunye nokunciphisa ubunzima .

Iinkcukacha Product

Kutheni Isithako Esingenashukela Sinokunceda Ukunciphisa Ubunzima?​​​​​​​

Ayizizo zonke izinto ezibangela i-hypoglycemic agents ezinegalelo ekunciphiseni umzimba. Isiphumo sokunciphisa umzimba se-tirzepatide sinxulumene ngokusondeleyo nomsebenzi wayo kwiindlela ze-GIP kunye ne-GLP-1 receptor.

Indlela yokubonisana ye-GLP-1 inokuchaphazela inkanuko yokutya kunye nokutya, kwaye indlela edibeneyo ye-GIP/GLP-1 inokuvelisa iziphumo ezibanzi zemetabolism. Ke ngoko, iimvavanyo zeklinikhi aziphandanga kuphela ukusebenza kwe-tirzepatide kulawulo lwe-glycemic kodwa kunye nokusetyenziswa kwayo ekulawuleni ubunzima.

Olu vavanyo lunike ubungqina bezonyango malunga nefuthe lokunciphisa umzimba le-tirzepatide kubantu abadala abatyebileyo okanye abatyebe kakhulu abangenayo i-type 2 diabetes.

I-Tirzepatide Powder Bulk ihlolwe kakhulu kwiinkqubo ezininzi zophuhliso lwezonyango. Ezi zifundo zihlolisise imiphumo ye-teirapatide kubunzima kunye nolawulo lwe-glycemic kumaqela ahlukeneyo abantu.

ISISHWANKATHELO-1: Uphononongo loLawulo loBunzima

I-SURMOUNT-1 yayiluphononongo lwezonyango kubantu abadala abatyebileyo okanye abatyebileyo, olubhalise abathathi-nxaxheba abangama-2,539 abangenaso isifo seswekile sohlobo lwesibini. Olu phononongo luthathe iiveki ezingama-72 kwaye ngokuyintloko luhlolisise imiphumo yeedosi ezahlukeneyo ze-teirapatide ekutshintsheni ubunzima.

Idatha epapashweyo ibonise ukuba zonke iidosi zovavanyo ze-teirapatide zibonise umkhwa obalulekileyo wokunciphisa umzimba xa kuthelekiswa ne-placebo, kunye neqela ledosi ye-15 mg ebonisa ukwehla kobunzima okuqhelekileyo malunga ne-20.9% kwiiveki ezingama-72, xa kuthelekiswa nokwehla kobunzima okuqhelekileyo malunga ne-3.1% kwiqela le-placebo.

ISISHWANKATHELO-2: Uphononongo lweSifo seswekile sohlobo lwesibini

I-SURMOUNT-2 iqhubekile nokuphonononga imiphumo ye-teirapatide kubunzima kubantu abadala abatyebileyo okanye abatyebileyo abanesifo seswekile sohlobo lwesibini. Olu phononongo luquke abathathi-nxaxheba abangama-938, lwalandelwa iiveki ezingama-72, lwaza lwathelekisa iziphumo ze-teirapatide 10 mg, 15 mg, kunye namaqela e-placebo.

Idatha ekhoyo esidlangalaleni ibonise ukuba kwiiveki ezingama-72, ukwehla kobunzima obuphakathi kumaqela e-teirapatide angama-10 mg kunye ne-15 mg bekumalunga ne-13.4% kunye ne-15.7%, ngokulandelelana, ngelixa ukwehla kobunzima obuphakathi kwiqela le-placebo bekumalunga ne-3.2%.

Olu phononongo lukwabonelela ngenkxaso yedatha kwizifundo zemetabolism ye-teirapatide kwizigulane ezinesifo seswekile ezityebileyo okanye ezityebileyo.

Izifundo eziNxulumene noLawulo lweGlycemic

Ukongeza kwizifundo zokulawula ubunzima, ukusetyenziswa kwe-teirapatide kwezonyango kukwagxila kwimiphumo yayo yokulawula i-glycemic. Uphononongo lwe-SURPASS-AP-Combo luquke izigulane ezingama-917 ezinesifo seswekile sohlobo lwesibini, ikakhulu ezivela eTshayina, eMzantsi Korea, eOstreliya naseIndiya, kunye nezingama-763 ezivela eTshayina. Olu phononongo luthelekise ulawulo lwe-glycemic kunye neendlela ezahlukeneyo zokuthatha i-teirapatide kunye nonyango lwe-insulin ye-glargine kanye ngemini.

Iziphumo zibonise ukuba ngexesha lonyango lweeveki ezingama-40, i-glycated hemoglobin (HbA1c) yehle kakhulu ukusuka ekuqaleni kuzo zonke iindidi zedosi yeTirzepatide. Inani eliphezulu lezigulana ezine-HbA1c <7.0% libonwe kuzo zonke iindidi zedosi yeTirzepatide.

Ezi ziphumo zophando ezifumaneka esidlangalaleni zibonisa ukuba indlela ye-Tirzepatide yokwenza i-agonist ye-GIP/GLP-1 receptor receptor agonist ayibalulekanga nje kuphela ekulawuleni ubunzima kodwa ikwanegalelo elikhulu kuphando kwisifo seswekile sohlobo lwesibini kunye nezifundo zolawulo lwe-glycemic.

*Olu lwazi lungasentla luqokelelwe ngokusekelwe kwidatha yophando lweklinikhi efumaneka esidlangalaleni kwaye lujoliswe kwimveliso kunye nereferensi yophando kuphela. Umthombo wedatha: Uvavanyo lweklinikhi lwe-SURMOUNT-1 (NEJM 2022)

Qhagamshelana nathi

Njengomthengisi weTirzepatide Powder Bulk , i-YTBIO ibonelela ngokuyintloko ngezinto zokwenza imveliso kunye neenkonzo ezinxulumene nayo kubathengi abathobela imigaqo efanelekileyo. Ukuba ufuna i-98% Tirzepatide Powder kwaye ungathanda ukufunda okungakumbi malunga namaxabiso kunye nolwazi lwemveliso, nceda unxibelelane neqela lethu.

​Tel:86-029-86478251 / 86-029-86119593

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